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B4 - Bilateral decision networks for eye and arm movements

We will investigate the role of intra- and inter-hemispheric interactions in the parietal areas LIP and PRR for decision-making related to eye and arm movements. By performing bi-hemispheric simultaneous recordings from these areas, in combination with unilateral reversible inactivation, this group will investigate how this bilateral neuronal network processes visual information to arrive at decisions related to the planning of saccadic eye and arm reaching movements, and how neuronal perturbations in the lesioned hemisphere affect the activity in the intact hemisphere. Spiking and local field potential (LFP) activity from these experiments will then be compared to concurrent primate fMRI experiments that will employ a similar design. These experiments will shed new light on how specific neuronal substrates from both hemispheres compete and collaborate for arriving at decisions for actions, and how the impaired inter-hemispheric balance causes inactivation-induced deficits.

Publications

Domínguez-Vargas AU**, Schneider L**, Wilke M*, Kagan I* (2017) Electrical microstimulation of the pulvinar biases saccade choices and reaction times in a time-dependent manner. Journal of Neuroscience (in press).** - shared first authors, * - shared senior authors

Principal investigators

Dr. Igor Kagan
German Primate Center
Decision and Awareness Group
Kellnerweg 4
37077 Göttingen
+49 (0)0551 3851 332
ikagan(at)dpz.eu

Prof. Dr. Melanie Wilke
University of Göttingen
Medical School
Dept. Cognitive Neurology
Robert-Koch-Str. 40
37075 Göttingen
+49 (0)551-3913131
melanie.wilke(at)med.uni-goettingen.de

Team

Danial Arabali
German Primate Center
Decision and Awareness Group
Kellnerweg 4
37077 Göttingen
+49 (0)551 385 1312
darabali(at)dpz.eu

Lukas Schneider
German Primate Center
Decision and Awareness Group
Kellnerweg 4
37077 Göttingen
lschneider(at)dpz.eu

research group websites

www.dpz.eu/dag