Scientific Goals

Understanding how the human brain realizes complex functions such as perception, communication, or the guidance of movement, requires an understanding of information processing at multiple levels, from synapses and neurons, to the processing of information in local microcircuits, up to large-scale interactions between distant brain areas. Invasive studies of the brains of non-human primates, used as models of the human brain, play a key role in research on the neuronal underpinnings of higher brain functions. They can take advantage of the similarity of the cognitive and behavioural repertoire of human and non-human primates and of the underlying brain architectures, which are both direct consequences of the phylogenetic proximity of the two groups.

In this DFG-funded research unit, we bring together primate neurophysiologists who unravel information processing in the brain of non-human primates with cutting edge methods. Sharing our complementary expertise within the research unit we will apply simultaneous electrophysiological and optical recordings from large population of neurons, use neuropharmacological approaches as well as functional brain imaging and use optogenetics to manipulate neuronal circuits. We strongly believe that answering the question of how highly developed brains generate complex functions requires an understanding of both information processing and its differences in distinct neuronal circuits (Research Area A), as well as an understanding of how signals are exchanged between circuits and areas (Research Area B).

Importantly, the neurobiological research program will be supplemented by activities to establish and develop the highest standards of animal experimentation and improve the public’s knowledge and acceptance of this core aspect of modern neuroscience research (primate welfare, ethics, and outreach projects). In an integrated graduate training program we will train the next generation of primate neurobiologists. Thus, the research unit will provide added value for primate neurobiology not only in terms of scientific but also of structural benefits.